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Current Drug Delivery

Editor-in-Chief

ISSN (Print): 1567-2018
ISSN (Online): 1875-5704

Review Article

Stem Cell Therapies for Intracerebral Hemorrhages

Author(s): Norihito Shimamura*, Naoya Mtsuda, Kosuke Ktayama, Kiyohide Kakuta, Takeshi Katagai, Masato Naraoka and Hiroki Ohkuma

Volume 14 , Issue 6 , 2017

Page: [758 - 765] Pages: 8

DOI: 10.2174/1567201813666160922115830

Price: $65

Abstract

Background: An insult due to intracerebral hemorrhage (ICH) is critical to patients. So, breakthroughs in ICH treatment are very important.

Objective: Advances in the stem cell treatment of stroke have been remarkable. And stem cell experimentation on ischemic stroke, however, preceded such work on ICH and did not emphasized ICH therapy.

Method: We review recent stem cell treatments for ICH, an experimental model of ICH, the medical care of ICH, and several stem cell therapies for ICH along with future prospects.

Results: Stem cell therapy for ICH is effective in rodent or animal models. For humans, only a small number of clinical trials have been done, and significant functional recovery was recorded.

Conclusion: We need to reveal the mechanism of stem cell therapy and develop a reliable, definitive treatment strategy for treatment of ICH. In the future, several types of stem cells will be available for the treatment of ICH.

Keywords: Functional recovery, intracerebral hemorrhage, migration, muse cell, proliferation, stem cell.

Graphical Abstract

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