Stem Cell Therapies for Intracerebral Hemorrhages

Title:Stem Cell Therapies for Intracerebral Hemorrhages

Volume: 14 Issue: 6

Author(s): Norihito Shimamura*, Naoya Mtsuda, Kosuke Ktayama, Kiyohide Kakuta, Takeshi Katagai, Masato Naraoka and Hiroki Ohkuma

Affiliation:

• Department of Neurosurgery, Hirosaki University Graduate School of Medicine, 5-Zaihuchou, Hirosaki Aomori Pref. 036-8562,Japan

Keywords: Functional recovery, intracerebral hemorrhage, migration, muse cell, proliferation, stem cell.

Abstract: Background: An insult due to intracerebral hemorrhage (ICH) is critical to patients. So, breakthroughs in ICH treatment are very important.

Objective: Advances in the stem cell treatment of stroke have been remarkable. And stem cell experimentation on ischemic stroke, however, preceded such work on ICH and did not emphasized ICH therapy.

Method: We review recent stem cell treatments for ICH, an experimental model of ICH, the medical care of ICH, and several stem cell therapies for ICH along with future prospects.

Results: Stem cell therapy for ICH is effective in rodent or animal models. For humans, only a small number of clinical trials have been done, and significant functional recovery was recorded.

Conclusion: We need to reveal the mechanism of stem cell therapy and develop a reliable, definitive treatment strategy for treatment of ICH. In the future, several types of stem cells will be available for the treatment of ICH.

Cite this article as:

Shimamura Norihito*, Mtsuda Naoya, Ktayama Kosuke, Kakuta Kiyohide, Katagai Takeshi, Naraoka Masato and Ohkuma Hiroki, Stem Cell Therapies for Intracerebral Hemorrhages, Current Drug Delivery 2017; 14(6) . https://dx.doi.org/10.2174/1567201813666160922115830

DOI https://dx.doi.org/10.2174/1567201813666160922115830	Print ISSN 1567-2018
Publisher Name Bentham Science Publisher	Online ISSN 1875-5704