Generic placeholder image

Current Topics in Medicinal Chemistry


ISSN (Print): 1568-0266
ISSN (Online): 1873-4294

Review Article

The Drug Targets and Antiviral Molecules for Treatment of Ebola Virus Infection

Author(s): Wenjiao Wu and Shuwen Liu

Volume 17, Issue 3, 2017

Page: [361 - 370] Pages: 10

DOI: 10.2174/1568026616666160829161318

Price: $65


Ebola virus (EBOV) is a highly pathogenic virus causing severe hemorrhagic fever with a high case fatality rate of 50% - 90% in humans. Without an approved vaccine or treatments, Ebola outbreak management has been limited to palliative care and barrier methods to prevent transmission. These approaches, however, have yet to end the 2014 outbreak of Ebola after its prolonged presence in West Africa. As with the increase of outbreaks, a significant effort has been made to develop promising countermeasures for the prevention and treatment of Ebola virus infection. In this review, development of therapeutics and potential inhibitors for Ebola virus infection will be discussed.

Keywords: Ebola virus, Therapeutics, Small molecules, Vaccines and antibody.

Graphical Abstract

Rights & Permissions Print Export Cite as
© 2023 Bentham Science Publishers | Privacy Policy