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Current Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

Intravenous and Regional Paclitaxel Formulations

Author(s): Rajendra Pawar, Ariella Shikanov, Boris Vaisman and Abraham J. Domb

Volume 11, Issue 4, 2004

Page: [397 - 402] Pages: 6

DOI: 10.2174/0929867043455981

Price: $65

Abstract

Paclitaxel has been proven to be effective against different types of cancer. A delivery system loaded with paclitaxel at tumor site should provide a high local concentration of the drug detrimental to malignant cells, which prevents the re-growth and metastasis of tumor. In this review, paclitaxel formulations for systemic and for intratumoral administration are discussed.

Keywords: paclitaxel, delivery systems, polymers, intratumoral delivery, formulations

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