Intravenous and Regional Paclitaxel Formulations

Rajendra      Pawar; Ariella      Shikanov; Boris      Vaisman; Abraham   J.   Domb

Abstract

Paclitaxel has been proven to be effective against different types of cancer. A delivery system loaded with paclitaxel at tumor site should provide a high local concentration of the drug detrimental to malignant cells, which prevents the re-growth and metastasis of tumor. In this review, paclitaxel formulations for systemic and for intratumoral administration are discussed.

Keywords: paclitaxel, delivery systems, polymers, intratumoral delivery, formulations