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Current Organic Chemistry


ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Review Article

Preparation of Acridine Derivatives Bearing Saturated Rings

Author(s): Andrzej F. Borowski

Volume 21, Issue 1, 2017

Page: [86 - 93] Pages: 8

DOI: 10.2174/1385272820666160817144522

Price: $65


This review presents possible routs of preparation of acridine derivatives con-taining saturated rings that can be obtained both as a result of traditional organic synthesis based on cyclization and condensation reactions and whenever available by partial or total catalytic (heterogeneous or homogeneous) hydrogenation of appropriate acridine derivatives. Methods of preparations of acridine derivatives bearing saturated rings are presented and discussed. The influence of resonance stabilisation energies of N-heteroaromatic and partly saturated N-heteroaromatic structures on hydrogenation susceptibility is discussed in relation to other aspects influencing saturation N-heteroaromatic versus carbocyclic rings.

Keywords: Acridine, acridine derivatives, resonance stabilisation energy, condensation reactions, catalytic heterogeneous hydrogenation, catalytic homogeneous hydrogenation, selective hydrogenation.

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