Abstract
In the previous parts of the series the antiviral agents used in genital herpes, genital HPV infection and therapeutic options in HIV infections were presented. The sexual contact is one of the major routes in the transmission of HBV and also possible modes of transmission of HCV. In this review we present the clinical indications, mechanisms of action, and side effects of presently available medication for the management of HBV and HCV infections. Currently a revolution is happening in the therapy of chronic hepatitis, especially caused by HCV. Direct-acting antivirals promise to open a new era in treating of chronic HCV infection. Efficacious, simplified and well tolerated interferon-free, and in some cases ribavirin-free regiments are available already and several other inhibitors currently are in the clinical trials.
Keywords: Antimicrobial resistance, Hepatitis B Virus, Hepatitis C Virus, Sexually transmitted diseases.
Mini-Reviews in Medicinal Chemistry
Title:Antiviral Medication in Sexually Transmitted Diseases. Part III: Hepatitis B, Hepatitis C
Volume: 17 Issue: 4
Author(s): Anna Majewska, Beata Mlynarczyk-Bonikowska, Magdalena Malejczyk, Slawomir Majewski and Grazyna Mlynarczyk
Affiliation:
Keywords: Antimicrobial resistance, Hepatitis B Virus, Hepatitis C Virus, Sexually transmitted diseases.
Abstract: In the previous parts of the series the antiviral agents used in genital herpes, genital HPV infection and therapeutic options in HIV infections were presented. The sexual contact is one of the major routes in the transmission of HBV and also possible modes of transmission of HCV. In this review we present the clinical indications, mechanisms of action, and side effects of presently available medication for the management of HBV and HCV infections. Currently a revolution is happening in the therapy of chronic hepatitis, especially caused by HCV. Direct-acting antivirals promise to open a new era in treating of chronic HCV infection. Efficacious, simplified and well tolerated interferon-free, and in some cases ribavirin-free regiments are available already and several other inhibitors currently are in the clinical trials.
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Majewska Anna, Mlynarczyk-Bonikowska Beata, Malejczyk Magdalena, Majewski Slawomir and Mlynarczyk Grazyna, Antiviral Medication in Sexually Transmitted Diseases. Part III: Hepatitis B, Hepatitis C, Mini-Reviews in Medicinal Chemistry 2017; 17 (4) . https://dx.doi.org/10.2174/1389557516666160808114408
DOI https://dx.doi.org/10.2174/1389557516666160808114408 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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