Antidotal Effects of Curcumin Against Agents-Induced Cardiovascular Toxicity

Title:Antidotal Effects of Curcumin Against Agents-Induced Cardiovascular Toxicity

Volume: 16 Issue: 1

Author(s): Tahereh Farkhondeh and Saeed Samarghandian

Affiliation:

Keywords: Antioxidant, cardiovascular, curcumin, toxic agents.

Abstract: Curcumin, the major phenolic compound in turmeric, shows preventive effects in various diseases. Curcumin is commonly found in rhizome of the Curcuma species and traditionally used in herbal medicine. Numeros studies has indicated that curcumin posses protective effects against toxic agents in various systems including cardiovascular. This study found that curcumin may be effective in cardiovascular diseases induced by toxic agents including Streptozotocin, Doxorubicin, Cyclosporin A, Methotrexate, Isoproterenol, Cadmium, Diesel exhaust particle, Nicotine, Hydrogen peroxide, and tert- Butyl hydroperoxide. However, due to the lake of information on human, further studies are needed to determine the efficacy of curcumin as an antidote agent. The present study aimed to critically review the recent literature data from that regarding the protective effects of curcumin against agents-induced cardiovascular toxicity.

Cite this article as:

Farkhondeh Tahereh and Samarghandian Saeed, Antidotal Effects of Curcumin Against Agents-Induced Cardiovascular Toxicity, Cardiovascular & Hematological Disorders-Drug Targets 2016; 16(1) . https://dx.doi.org/10.2174/1871529X16666160802144510