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Current Protein & Peptide Science


ISSN (Print): 1389-2037
ISSN (Online): 1875-5550

Review Article

Resistance (R) Genes: Applications and Prospects for Plant Biotechnology and Breeding

Author(s): Valesca Pandolfi, Jose Ribamar Costa Ferreira Neto, Manasses Daniel da Silva, Lidiane Lindinalva Barbosa Amorim, Ana Carolina Wanderley-Nogueira, Roberta Lane de Oliveira Silva, Ederson Akio Kido, Sergio Crovella and Ana Maria Benko Iseppon

Volume 18, Issue 4, 2017

Page: [323 - 334] Pages: 12

DOI: 10.2174/1389203717666160724195248

Price: $65


The discovery of novel plant resistance (R) genes (including their homologs and analogs) opened interesting possibilities for controlling plant diseases caused by several pathogens. However, due to environmental pressure and high selection operated by pathogens, several crop plants have lost specificity, broad-spectrum or durability of resistance. On the other hand, the advances in plant genome sequencing and biotechnological approaches, combined with the increasing knowledge on Rgenes have provided new insights on their applications for plant genetic breeding, allowing the identification and implementation of novel and efficient strategies that enhance or optimize their use for efficiently controlling plant diseases. The present review focuses on main perspectives of application of R-genes and its co-players for the acquisition of resistance to pathogens in cultivated plants, with emphasis on biotechnological inferences, including transgenesis, cisgenesis, directed mutagenesis and gene editing, with examples of success and challenges to be faced.

Keywords: Disease resistance, plant pathogen, genetic modification, directed mutagenesis.

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