Recent Advances in the Applications of SAMP/RAMP as Chiral Auxiliaries in Asymmetric Synthesis

Title:Recent Advances in the Applications of SAMP/RAMP as Chiral Auxiliaries in Asymmetric Synthesis

Volume: 14 Issue: 1

Author(s): Majid M. Heravi, Vahideh Zadsirjan and Mansoureh Daraie

Affiliation:

Keywords: Chiral auxiliaries, asymmetric synthesis, SAMP/RAMP, stereoselective synthesis.

Abstract: Nowadays, the stereoselective synthesis of naturally occurring compounds showing biological activity has attracted much attention and stirred up the interest of organic synthetic chemists. Apparently, the multi-step total synthesis of such complex molecules bearing several stereogenic centers demands the development of the efficient and operational strategies for the induction of chirality in a certain step (steps). Among the most practical approaches in the area of stoichiometric asymmetric synthesis, the SAMP/RAMP hydrazone methodology has been found to be a powerful tool in the synthesis of numerous naturally occurring, and bioactive compounds. In this report, we try to highlight the applications of this methodology in asymmetric synthesis.

Cite this article as:

Heravi M. Majid, Zadsirjan Vahideh and Daraie Mansoureh, Recent Advances in the Applications of SAMP/RAMP as Chiral Auxiliaries in Asymmetric Synthesis, Current Organic Synthesis 2017; 14 (1) . https://dx.doi.org/10.2174/1570179413666160624112433