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Current Bioactive Compounds

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ISSN (Print): 1573-4072
ISSN (Online): 1875-6646

Research Article

Chemical Research and Evaluation of the Antioxidant Activity of the Flowers of Annona coriacea Mart. (Annonaceae)

Author(s): Cicera J. Camilo, Rafael P. Caldas, Sarah S. Damasceno, Cristiane M.U. Lopes, Sheyla C.X. Almeida, Jose G.M. da Costa and Fabiola F.G. Rodrigues

Volume 13 , Issue 1 , 2017

Page: [66 - 70] Pages: 5

DOI: 10.2174/1573407212666160620093125

Price: $65

Abstract

Background: The Annona coriacea Mart. species, popularly known as "araticum", "marolo" and "araticum-liso", is distributed throughout the Cerrado in the North and Northeast of Brazil, especially in Ceará. The aim of this study is to investigate the chemical composition and evaluate the antioxidant properties of flowers of Annona coriacea.

Methods: The crude extract was obtained by maceration in 95% ethanol. A chemical screening was performed to identify classes of secondary metabolites. Quantification of flavonoids was performed by measuring the absorbance of the complex formed between the flavonoid and the aluminum color reagent. The determination of phenolic compounds was performed using the Folin-Ciocalteu reagent. The antioxidant activity was carried out from the elimination of DPPH free radicals.

Results: Chemical prospecting revealed the presence of classes of flavonoids and tannins. The quantification of flavonoids showed content of 2.17 ± 0,90 µgEqQ/g and phenols of 0.09 ± 0,01 µgEqAG/g. The antioxidant result showed IC50 value of 61.04 ± 22.10 g/mL and control with BHT of 3.16 ± 2.20 g/mL.

Conclusion: These results indicate the need for further studies involving this species aiming to obtain better information of chemical and biological properties.

Keywords: Phytotherapy, extract, prospecting, quantification, flavonoids, phenols.

Graphical Abstract

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