Abstract
Background: In tissue engineering applications, advanced membrane systems provide useful and adaptable biomimetic microenvironment able to sustain cell viability and functions, enabling the delivery and diffusion of biochemical factors, cell nutrients, and products, and mimicking the natural biological extracellular matrix. Proper cell-material interactions favour cell adhesion and trigger cell growth, migration, proliferation, differentiation and functional activation. The wide availability of biocompatible polymers offers the possibility to develop membranes with tuned morphological, physico-chemical, mechanical and transport properties for targeted tissues.
Objective: In this review, an in-depth examination of how the membrane properties are able to influence and direct the cellular morpho-functional behaviour of specific engineered tissues is discussed. Furthermore, an overview of the advanced membrane systems, in different configuration and composition, for the biofabrication of tissues and organs is reported.Keywords: Polymeric membranes, properties, cell-material interactions, biodegradable membranes, non-degradable membranes, biohybrid systems, tissue engineering.
Current Organic Chemistry
Title:Advanced Membrane Systems for Tissue Engineering
Volume: 21 Issue: 17
Author(s): Simona Salerno*, Sabrina Morelli and Loredana De Bartolo
Affiliation:
- Institute on Membrane Technology, National Research Council of Italy, ITM-CNR c/o University of Calabria, via P. Bucci cubo 17/C, I-87036 Rende (CS),Italy
Keywords: Polymeric membranes, properties, cell-material interactions, biodegradable membranes, non-degradable membranes, biohybrid systems, tissue engineering.
Abstract: Background: In tissue engineering applications, advanced membrane systems provide useful and adaptable biomimetic microenvironment able to sustain cell viability and functions, enabling the delivery and diffusion of biochemical factors, cell nutrients, and products, and mimicking the natural biological extracellular matrix. Proper cell-material interactions favour cell adhesion and trigger cell growth, migration, proliferation, differentiation and functional activation. The wide availability of biocompatible polymers offers the possibility to develop membranes with tuned morphological, physico-chemical, mechanical and transport properties for targeted tissues.
Objective: In this review, an in-depth examination of how the membrane properties are able to influence and direct the cellular morpho-functional behaviour of specific engineered tissues is discussed. Furthermore, an overview of the advanced membrane systems, in different configuration and composition, for the biofabrication of tissues and organs is reported.Export Options
About this article
Cite this article as:
Salerno Simona*, Morelli Sabrina and Bartolo De Loredana, Advanced Membrane Systems for Tissue Engineering, Current Organic Chemistry 2017; 21 (17) . https://dx.doi.org/10.2174/1385272820666160617092944
DOI https://dx.doi.org/10.2174/1385272820666160617092944 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
Call for Papers in Thematic Issues
Advances of Heterocyclic Chemistry with Pesticide Activity
Global food safety and security will continue to be a global concern for the next 50 years and beyond. Plant diseases have had a significant impact on food safety and security throughout the entire food chain, from primary production to consumption. While conventional chemical pesticides have been traditionally used for ...read more
Calculation design of covalent/metal organic framework based catalysts
This research area combines theoretical computation and screening with machine learning for the design of covalent/metal organic framework-based catalysts, bridging the disciplines of organic chemistry, physical chemistry, computational chemistry, materials science, and machine learning. It covers several critical aspects: designing and synthesizing organic catalysts for improved performance, applying computational methods ...read more
Carbohydrates conversion in biofuels and bioproducts
Biomass pretreatment, hydrolysis, and saccharification of carbohydrates, and sugars bioconversion in biofuels and bioproducts within a biorefinery framework. Carbohydrates derived from woody biomass, agricultural wastes, algae, sewage sludge, or any other lignocellulosic feedstock are included in this issue. Simulation, techno-economic analysis, and life cycle analysis of a biorefinery process are ...read more
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
New Approaches With Natural Product Drugs for Overcoming Multidrug Resistance in Cancer
Current Pharmaceutical Design Epigenetic Remodeling of Chromatin Architecture: Exploring Tumor Differentiation Therapies in Mesenchymal Stem Cells and Sarcomas
Current Stem Cell Research & Therapy Therapeutic Implications of Superoxide Dismutase And Its Importance in Kinase Drug Discovery
Current Topics in Medicinal Chemistry FoxO1 Inhibitors: The Future Medicine for Metabolic Disorders?
Current Diabetes Reviews Cancer Therapy By Targeting Hypoxia-Inducible Factor-1
Current Cancer Drug Targets Epigenetic Aberrations and Targeted Epigenetic Therapy of Esophageal Cancer
Current Cancer Drug Targets Signaling Mechanisms Underlying Aβ Toxicity: Potential Therapeutic Targets for Alzheimers Disease
CNS & Neurological Disorders - Drug Targets Recent Inventions on Receptor Tyrosine Kinase RET Modulation
Recent Patents on Biotechnology Anticancer Properties of Amino Acid and Peptide Derivatives of Mycophenolic Acid
Anti-Cancer Agents in Medicinal Chemistry The Exploitation of Toll-like Receptor 3 Signaling in Cancer Therapy
Current Pharmaceutical Design The Ubiquitin-Proteasome System as a Prospective Molecular Target for Cancer Treatment and Prevention
Current Protein & Peptide Science Morphine as a Potential Oxidative Stress-Causing Agent
Mini-Reviews in Organic Chemistry A Combination of Two Antioxidants (An SOD Mimic and Ascorbate) Produces a Pro-Oxidative Effect Forcing Escherichia coli to Adapt Via Induction of oxyR Regulon
Anti-Cancer Agents in Medicinal Chemistry Ginkgo Biloba Extract (EGb 761) in Alzheimers Disease: Is there Any Evidence?
Current Alzheimer Research The Forkhead Transcription Factor FOXO3a Controls Microglial Inflammatory Activation and Eventual Apoptotic Injury through Caspase 3
Current Neurovascular Research Targeting Monoamine Oxidases with Multipotent Ligands: An Emerging Strategy in the Search of New Drugs Against Neurodegenerative Diseases
Current Medicinal Chemistry Current Prodrug Design for Drug Discovery
Current Pharmaceutical Design Clinical Pharmacology of Cyclophosphamide and Ifosfamide
Current Drug Therapy Neuroprotective and Preventative Effects of Molecular Hydrogen
Current Pharmaceutical Design Macroautophagy as a Target of Cancer Therapy
Current Cancer Therapy Reviews