Abstract
Psoriasis is a common skin disorder characterized by hyper proliferation of keratinocytes. Although the exact pathophysiology of psoriasis is not entirely understood, immune system and its interaction with nervous system have been postulated and investigated as the underlying mechanism. The interaction between these two systems through cholinergic anti-inflammatory pathway and also endocannabinoid system, may suggest cannabinoids as potential addition to antipsoriatic armamentarium.
Keywords: Psoriasis, immunomodulation, cannabidiol, endocannabinoids, vagal nerve stimulation.
Current Clinical Pharmacology
Title:Cannabis for Refractory Psoriasis—High Hopes for a Novel Treatment and a Literature Review
Volume: 11 Issue: 2
Author(s): Nima Derakhshan and Mahboubeh Kazemi
Affiliation:
- ,0
Keywords: Psoriasis, immunomodulation, cannabidiol, endocannabinoids, vagal nerve stimulation.
Abstract: Psoriasis is a common skin disorder characterized by hyper proliferation of keratinocytes. Although the exact pathophysiology of psoriasis is not entirely understood, immune system and its interaction with nervous system have been postulated and investigated as the underlying mechanism. The interaction between these two systems through cholinergic anti-inflammatory pathway and also endocannabinoid system, may suggest cannabinoids as potential addition to antipsoriatic armamentarium.
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Cite this article as:
Derakhshan Nima and Kazemi Mahboubeh, Cannabis for Refractory Psoriasis—High Hopes for a Novel Treatment and a Literature Review, Current Clinical Pharmacology 2016; 11(2) . https://dx.doi.org/10.2174/1574884711666160511150126
DOI https://dx.doi.org/10.2174/1574884711666160511150126 |
Print ISSN 1574-8847 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3938 |
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