Abstract
Endothelial to mesenchymal transition (EndMT) is a poorly understood phenomenon that results in normal endothelial cells acquiring a mesenchymal phenotype. EndMT has been observed in a number of pathological conditions, from cancer to fibrosis to cardiovascular disease and the process itself may play an important mechanistic role in the development of these disease states.
Keywords: Endothelial cell, endothelial to mesenchymal transition, EndMT, TGFβ, FGF.
Current Drug Targets
Title:Future Targets in Endothelial Biology: Endothelial Cell to Mesenchymal Transition
Volume: 17 Issue: 15
Author(s): Pei-Yu Chen and Michael Simons
Affiliation:
Keywords: Endothelial cell, endothelial to mesenchymal transition, EndMT, TGFβ, FGF.
Abstract: Endothelial to mesenchymal transition (EndMT) is a poorly understood phenomenon that results in normal endothelial cells acquiring a mesenchymal phenotype. EndMT has been observed in a number of pathological conditions, from cancer to fibrosis to cardiovascular disease and the process itself may play an important mechanistic role in the development of these disease states.
Export Options
About this article
Cite this article as:
Chen Pei-Yu and Simons Michael, Future Targets in Endothelial Biology: Endothelial Cell to Mesenchymal Transition, Current Drug Targets 2016; 17 (15) . https://dx.doi.org/10.2174/1389450117666160502151308
DOI https://dx.doi.org/10.2174/1389450117666160502151308 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
Call for Papers in Thematic Issues
New drug therapy for eye diseases
Eyesight is one of the most critical senses, accounting for over 80% of our perceptions. Our quality of life might be significantly affected by eye disease, including glaucoma, diabetic retinopathy, dry eye, etc. Although the development of microinvasive ocular surgery reduces surgical complications and improves overall outcomes, medication therapy is ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Long-Term Outcome of Cardio Respiratory Exercise Performance After Surgery
Current Respiratory Medicine Reviews Cardioprotection Techniques: Preconditioning, Postconditioning and Remote Con-ditioning (Basic Science)
Current Pharmaceutical Design The Vectorcardiogram and the Main Dromotropic Disturbances
Current Cardiology Reviews The Spatial QRS-T Angle: Implications in Clinical Practice
Current Cardiology Reviews Cardiac Role of the Transcription Factor NF-κB
Cardiovascular & Hematological Disorders-Drug Targets The Right Ventricle: Biologic Insights and Response to Disease: Updated
Current Cardiology Reviews Transcription Factor CHF1/Hey2 Regulates Specific Pathways in Serum Stimulated Primary Cardiac Myocytes: Implications for Cardiac Hypertrophy
Current Genomics Critical Congenital Heart Disease in Neonates: A Review Article
Current Pediatric Reviews Arterial Duct Stenting in Congenital Heart Disease with Duct-Dependent Pulmonary Circulation
Current Pediatric Reviews Smoking and Congenital Heart Disease: The Epidemiological and Biological Link
Current Pharmaceutical Design Potential Roles of MyomiRs in Cardiac Development and Related Diseases
Current Cardiology Reviews Notch Signaling in Cardiovascular Disease and Calcification
Current Cardiology Reviews Genome-wide Analysis of Myelodysplastic Syndromes
Current Pharmaceutical Design Editorial (Thematic Issue: Cardiovascular Drug Therapy in Paediatric Age: From Metabolomics to Clinical Practice)
Current Medicinal Chemistry A Comparative Effectiveness Systematic Review and Meta-analysis of Drugs for the Prophylaxis of Junctional Ectopic Tachycardia
Current Cardiology Reviews Fragmented ECG as a Risk Marker in Cardiovascular Diseases
Current Cardiology Reviews Complications of the Chest Wall and the Respiratory System After Surgery and Functional Performance
Current Respiratory Medicine Reviews Diagnostic Cardiac Catheterization in the Pediatric Population
Current Cardiology Reviews Mechanical Ventilation Following Cardiac Surgery in Children
Current Respiratory Medicine Reviews Atrial Macroreentry in Congenital Heart Disease
Current Cardiology Reviews