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Current HIV Research


ISSN (Print): 1570-162X
ISSN (Online): 1873-4251

Assessment of the Accuracy of Whole Blood/Serum Rapid Point-of-Care HIV Three Dot Test for Oral Fluid Specimens

Author(s): N. Rakesh, Shakilla Shetty, S. Sujatha, Shivani Sharma and Ankit Saxena

Volume 14 , Issue 4 , 2016

Page: [354 - 359] Pages: 6

DOI: 10.2174/1570162X14666160321120123

Price: $65


Background: Saliva rapid point of care HIV tests have proven advantages over blood-based HIV tests in terms of quality, rapidity and convenience.

Aim: To assess the sensitivity, specificity and reproducibility of saliva samples using the serum/ whole blood rapid test and to compare it with serum specimens.

Material & Methods: 52 seropositive and 52 seronegative patients were included in the study. Stimulated and unstimulated saliva samples were collected and tested using the serum/ whole blood signal HIV THREE DOT rapid test (span diagnostics).

Results: The sensitivity, specificity, positive predictive value and negative predictive value of the test was found to be 100% for saliva samples.

Conclusion: Saliva samples can be used as a substitute to serum/whole blood for HIV testing. It can be done using the serum/whole blood kits which are cheaper and readily available thus broadening the reach of testing programs in resource limited settings.

Keywords: HIV testing, point of care test, serum/whole blood tri dot rapid test, oral fluid, dental setting.

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