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Current Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

Morin: A Promising Natural Drug

Author(s): Anna Caselli, Paolo Cirri, Alice Santi and Paolo Paoli

Volume 23 , Issue 8 , 2016

Page: [774 - 791] Pages: 18

DOI: 10.2174/0929867323666160106150821

Price: $65

Abstract

Morin is a natural polyphenol, originally isolated from members of the Moraceae family that can be extracted from leaves, fruits, stems and branches of numerous plants. Several evidence have demonstrated that Morin could have a beneficial effect on several human diseases. In fact, Morin exerts antioxidant, antidiabetic, anti-inflammatory, antitumoral, antihypertensive, antibacterial, hypouricemic, and neuroprotective effects, by modulating the activity of many enzymes. In some cases, Morin shows a systemic protective action, reducing negative side effects of several drugs, without interfering with their functions. In addition, in vitro and in vivo studies demonstrated that Morin exhibits very low toxicity levels and its chronic administration is well tolerated. All these findings suggest that Morin could be used, either alone or in combination with other drugs, to prevent many human pathologies.

Keywords: Morin, flavonoid, polyphenol, natural drug, anti-oxidant, anti-diabetic, anti-inflammatory.


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