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Current Computer-Aided Drug Design

Editor-in-Chief

ISSN (Print): 1573-4099
ISSN (Online): 1875-6697

Modeling Bacterial Infection Phenomena

Author(s): Lemont B. Kier

Volume 11, Issue 4, 2015

Page: [321 - 324] Pages: 4

DOI: 10.2174/1573409912666151218155921

Price: $65

Abstract

A series of cellular automata models of bacteria were created, where encounters with models of the immune system and a model of an antibiotic drug were present. The dose of the antibiotic, its potency and the timeliness of its administration were variables. The emergence of antibiotic resistance by the bacteria was an outcome associated with the administration of the drug. The models created in these studies were found to closely relate to clinical experiences, making the general model useful for further simulation studies.

Keywords: Bacteria, cellular automata, immunity effect, antibiotics.


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