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Current Pharmaceutical Design


ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Cardiac Chamber Volumetric Assessment Using 3D Ultrasound - A Review

Author(s): Joao Pedrosa, Daniel Barbosa, Nuno Almeida, Olivier Bernard, Johan Bosch and Jan D`hooge

Volume 22 , Issue 1 , 2016

Page: [105 - 121] Pages: 17

DOI: 10.2174/1381612822666151109112652

Price: $65


When designing clinical trials for testing novel cardiovascular therapies, it is highly relevant to understand what a given technology can provide in terms of information on the physiologic status of the heart and vessels. Ultrasound imaging has traditionally been the modality of choice to study the cardiovascular system as it has an excellent temporal resolution; it operates in real-time; it is very widespread and - not unimportant - it is cheap. Although this modality is mostly known clinically as a two-dimensional technology, it has recently matured into a true three-dimensional imaging technique. In this review paper, an overview is given of the available ultrasound technology for cardiac chamber quantification in terms of volume and function and evidence is given why these parameters are of value when testing the effect of new cardiovascular therapies.

Keywords: Cardiac function, Cardiac volume, 3D echocardiography, Segmentation, Automated analysis, Commercial solutions, Validation studies.

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