摘要
几十年以来,多酚被认为是健全的天然治疗化合物。虽然有几种多酚用于治疗癌症和其它疾病的特殊应用,但它们需要特定的载体以达到靶细胞。最近,已经开发了许多纳米级的新技术,例如纳米颗粒,纳米胶囊和纳米纤维,其可以提供用于医疗目的的多酚的靶向传递。 这项工作总结了多酚在癌症治疗中纳米传送技术的当前趋势,并概述其能力和已经取得的重大改进。 特别强调是用于生产这类药物传送系统纳米结构的材料和制造方法。
关键词: 药物传送
Current Drug Targets
Title:Trends in Nanomaterials and Processing for Drug Delivery of Polyphenols in the Treatment of Cancer and Other Therapies
Volume: 18 Issue: 2
Author(s): Joaquim Ciurana, Ciro A. Rodríguez
Affiliation:
关键词: 药物传送
摘要: For decades polyphenols have been considered to be sound, naturally occurring therapeutic compounds. While there are several polyphenols with special applications used in the treatment of cancer and other diseases, they need a specific carrier in order to reach the cells targeted for treatment. Recently, a number of new technologies have been developed on a nanoscale, such as nanoparticles, nanocapsules and nanofibers that can provide targeted delivery of polyphenols for medical purposes. This work summarizes the current trends in nanoscale delivery technology for polyphenols in cancer treatment and outlines its capabilities and the significant improvements that have been made. Special emphasis is given to the materials and to the manufacturing processes used to produce these kinds of drug delivery system nanostructures.
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Cite this article as:
Joaquim Ciurana, Ciro A. Rodríguez , Trends in Nanomaterials and Processing for Drug Delivery of Polyphenols in the Treatment of Cancer and Other Therapies, Current Drug Targets 2017; 18 (2) . https://dx.doi.org/10.2174/1389450116666151102094738
DOI https://dx.doi.org/10.2174/1389450116666151102094738 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
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