Cell-in-cell phenomenon: A New Paradigm in Life Sciences.

Title:Cell-in-cell phenomenon: A New Paradigm in Life Sciences.

Volume: 15 Issue: 9

Author(s): X. Wang

Affiliation:

• Institute of Life Sciences, the Key Laboratory of Normal Aging & Geriatric, the Chinese PLA General Hospital, Beijing 100853, P.R. China.,China

Keywords: Cell-in-cell, cell-in-cell death, cell model, cell diversity, cell evolution.

Abstract: Cell-in-cell, a phenomenon characterized by one or more viable cells entering actively into another cell, was observed more than a century and has only attracted more attention in recent years and is becoming a new hot topic in the biological field, owing its biological significance in evolutionary as well as physiological and pathological relevance in development, homeostasis and diseases. In this paper we focus on the diversity, evolutionary conservatism and clinical implication of cell-in-cell as well as latest opinions on the research strategies. Based on the findings from our laboratory and other research groups three working models of cell-in-cell are also proposed.

Cite this article as:

Wang X., Cell-in-cell phenomenon: A New Paradigm in Life Sciences., Current Molecular Medicine 2015; 15(9) . https://dx.doi.org/10.2174/1566524015666151026095730