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Endocrine, Metabolic & Immune Disorders - Drug Targets


ISSN (Print): 1871-5303
ISSN (Online): 2212-3873

Hypopituitarism in Neurocritical Patients: A Case Report

Author(s): Michele Iovino, Nicola Iovine, Fiorentino Mondillo, Edoardo Guastamacchia, Brunclla Licchelli, Vito A. Giagulli and Vincenzo Triggiani

Volume 16, Issue 1, 2016

Page: [28 - 31] Pages: 4

DOI: 10.2174/1871530315666150930121912

Price: $65


Background: Besides changes in pituitary hormones secretion observed during the acute phase of stroke as an adaptive response to injury or an effect of drugs, a true hypopituitarism due to ischemic and/or hemorrhagic damage at the hypothalamus and/or pituitary gland can develop after a stroke.

Case Report: We report a case of a 72-year-old woman showing clinical signs and laboratory data suggesting a secondary adrenal insufficiency following a recent acute brain ischemia. Cortisone therapy significantly improved this pituitary dysfunction.

Conclusions: Clinicians must pay attention to the hypothalamic-pituitary axis in neurocritical patients because hormonal replacement therapy may be life-saving.

Keywords: Adrenal insufficiency, hyponatremia, hypopituitarism, neuro-critical patients.

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