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Current Medicinal Chemistry


ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

Inflammatory Biomarkers in Peripheral Artery Disease: Diagnosis, Prognosis, and Therapeutic Challenges

Author(s): Yuichi Ozaki, Toshio Imanishi and Takashi Akasaka

Volume 22 , Issue 23 , 2015

Page: [2744 - 2753] Pages: 10

DOI: 10.2174/0929867322666150630141200

Price: $65


Peripheral artery disease (PAD) is an inflammatory disease caused by atherosclerosis. It has been demonstrated that PAD is related to chronic inflammation. While conventional risk factors lead to the pathogenesis and progression of PAD, the role of novel inflammatory biomarkers in relation to PAD is being increasingly recognized. The novel biomarkers for PAD may allow for earlier screening and detection, suppression of disease progression, and development of new therapeutic approaches. In this review, inflammatory biomarkers that should be contributory to diagnosis, prognosis, and avenues for therapeutic challenges in PAD are summarized.

Keywords: Biomarker, diagnosis, peripheral artery disease, prognosis, therapy.

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