Abstract
AIDS remains one of the world’s most serious health challenges, with 35 million people living with HIV worldwide at the end of 2013. HIV sexual transmission accounts for the overwhelming majority of people newly infected, making genital and rectal mucosal tissues the major sites of infection. This review focuses on the role of the female genital epithelial cells in the establishment of HIV infection.
Keywords: Epithelial cells, female genital tract, HIV-1, innate immunity, microbicides, semen, sexually transmitted agents.
Current HIV Research
Title:Pivotal Role of the Genital Epithelial Cells in HIV-1 Transmission
Volume: 13 Issue: 6
Author(s): Amelie De Saint Jean, Thomas Bourlet and Olivier Delezay
Affiliation:
Keywords: Epithelial cells, female genital tract, HIV-1, innate immunity, microbicides, semen, sexually transmitted agents.
Abstract: AIDS remains one of the world’s most serious health challenges, with 35 million people living with HIV worldwide at the end of 2013. HIV sexual transmission accounts for the overwhelming majority of people newly infected, making genital and rectal mucosal tissues the major sites of infection. This review focuses on the role of the female genital epithelial cells in the establishment of HIV infection.
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Cite this article as:
De Saint Jean Amelie, Bourlet Thomas and Delezay Olivier, Pivotal Role of the Genital Epithelial Cells in HIV-1 Transmission, Current HIV Research 2015; 13 (6) . https://dx.doi.org/10.2174/1570162X13666150624100339
DOI https://dx.doi.org/10.2174/1570162X13666150624100339 |
Print ISSN 1570-162X |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4251 |
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Management of HIV: Management of HIV: old challenges and new needs
The aim of this thematic issue is to provide the most recent updates regarding the effective management of HIV infection. Antiretroviral therapy (ART) has significantly decreased HIV-related mortality, leading to an enhancement in the quality of life and life expectancy for people living with HIV (PLWH). Despite the numerous advancements ...read more
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