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Current Pharmaceutical Design

Editor-in-Chief

ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

GABAB Agonists for the Treatment of Alcohol Use Disorder

Author(s): Antonio Mirijello, Fabio Caputo, Gabriele Vassallo, Benjamin Rolland, Claudia Tarli, Antonio Gasbarrini and Giovanni Addolorato

Volume 21, Issue 23, 2015

Page: [3367 - 3372] Pages: 6

DOI: 10.2174/1381612821666150619091858

Price: $65

Abstract

Almost 10% of the world’s population is affected by alcohol use disorder (AUD). The combination between psychosocial intervention and pharmacological treatment seems to be the most effective approach for patients affected by AUD. Among effective drugs useful in the treatment of AUD, GABAB-ergic medications have been tested with encouraging results (i.e. sodium oxybate, baclofen, gabapentin, pregabalin and tiagabine). The present review will summarize available data on these medications.

Keywords: Alcohol use disorder, craving, GABAB agonists, pharmacological treatment.


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