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Combinatorial Chemistry & High Throughput Screening


ISSN (Print): 1386-2073
ISSN (Online): 1875-5402

Simple and Efficient Route Toward Ambient Preparation of Pyrimido[b]Quinolinetriones Using Copper (I) Iodide Nanoparticles in Aqueous Media

Author(s): Shahrzad Abdolmohammadi and Zahra Aghaei-Meybodi

Volume 18 , Issue 9 , 2015

Page: [911 - 916] Pages: 6

DOI: 10.2174/1386207318666150525094234

Price: $65


A simple and efficient synthesis of pyrimido[b]quinolinetriones is introduced using copper (I) iodide nanoparticles (CuI NPs) as an efficient heterogeneous catalyst in green media-water. The catalyst was prepared through the simple precipitation route and well characterized by various techniques such as XRD and SEM. The mild reaction conditions, using aqueous medium, reusability of the catalyst, simple reaction work-up and excellent yields of products make the present protocol sustainable and advantageous compared to the conventional methods.

Keywords: Aqueous media, CuI nanoparticles (CuI NPs), pyrimido[5, 4-b]quinolinetriones, tandem Knoevenagel-Michael condensation.

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