Abstract
Malondialdehyde (MDA) is one of the most common biomarkers of oxidative stress and is used for the diagnosis of many diseases. This work aims to review the reaction used for the derivatization of MDA, the parameters affecting adduct formation, and a number of recently published analytical methods for quantification of MDA in biological samples. A brief discussion of the reliability of MDA as an oxidative stress biomarker is also provided.
Keywords: Oxidative stress, biomarker, malondialdehyde, serum analysis, bioanalysis, review.
Current Pharmaceutical Analysis
Title:Critical Review of Malondialdehyde Analysis in Biological Samples
Volume: 12 Issue: 1
Author(s): Maryam Khoubnasabjafari, Khalil Ansarin and Abolghasem Jouyban
Affiliation:
Keywords: Oxidative stress, biomarker, malondialdehyde, serum analysis, bioanalysis, review.
Abstract: Malondialdehyde (MDA) is one of the most common biomarkers of oxidative stress and is used for the diagnosis of many diseases. This work aims to review the reaction used for the derivatization of MDA, the parameters affecting adduct formation, and a number of recently published analytical methods for quantification of MDA in biological samples. A brief discussion of the reliability of MDA as an oxidative stress biomarker is also provided.
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Cite this article as:
Khoubnasabjafari Maryam, Ansarin Khalil and Jouyban Abolghasem, Critical Review of Malondialdehyde Analysis in Biological Samples, Current Pharmaceutical Analysis 2016; 12 (1) . https://dx.doi.org/10.2174/1573412911666150505185343
DOI https://dx.doi.org/10.2174/1573412911666150505185343 |
Print ISSN 1573-4129 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-676X |
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