Generic placeholder image

Current Stem Cell Research & Therapy

Editor-in-Chief

ISSN (Print): 1574-888X
ISSN (Online): 2212-3946

Chemical and physical factors influencing the dynamics of differentiation in embryonic stem cells

Author(s): Saras Jyoti and Simran Tandon

Volume 10, Issue 6, 2015

Page: [477 - 491] Pages: 15

DOI: 10.2174/1574888X10666150416113055

Price: $65

Abstract

Differentiating embryonic stem cells into a specific lineage or cell type is one of the most investigated areas of stem cell research; however it is wrought with hurdles. The differentiation process during embryogenesis is greatly influenced by physiochemical factors. They direct key genes for lineage commitment, which in turn are responsible for patterning into highly organized tissues resulting in organ formation. In this review, we have focused on the influence of physiochemical factors on the differentiation process in embryonic stem cells, which mimics, embryogenesis in vivo.

Keywords: Cell fate, differentiation, embryo-genesis, embryonic stem cells, specification.


Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy