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Current Organic Chemistry


ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Polymer – Nanoparticle Assemblies for Array Based Sensing

Author(s): Brian Creran, Uwe H.F. Bunz and Vincent M. Rotello

Volume 19, Issue 12, 2015

Page: [1054 - 1062] Pages: 9

DOI: 10.2174/1385272819666150318221301

Price: $65


Sensing clinically relevant biomolecules is crucial for the detection and prevention of disease. Currently used detection methods tend to be expensive, time intensive, and specific for only one particular biomolecule of interest. Nanoparticle-based arrays using conjugated polymers have emerged as an analytical and potential clinical tool, allowing detection of a wide range of biomolecules using selective, not specific, sensor components. In this report, we highlight recent progress in nanoparticle - polymer sensor arrays in both the fundamental understanding of how the sensor arrays function as well as the detection of clinically relevant bacteria and cells.

Keywords: Biosensing, conjugated polymers, displacement assay, nanoparticles.

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