Abstract
A 41-year-old woman with Major Depressive Disorder-Recurrent was treated with topiramate at 150 mg/day. After this administration, she developed intense pruritus and skin lesions due to scratching. Consequently, she was weaned off topiramate and the lesions regressed. Pruritus and cutaneous lesions are extremely rare side effects of topiramate, so we report an interesting case of skin reaction to this drug.
Keywords: Depression, mood stabilizers, pruritus, side effects, skin disorders, topiramate.
CNS & Neurological Disorders - Drug Targets
Title:Can Topiramate Induce Pruritus? A Case Report and Review of Literature
Volume: 14 Issue: 3
Author(s): Maria S. Signorelli, Maria Cinconze, Maria R. Nasca, Monica Marino, Giovanni Martinotti, Massimo Di Giannantonio and Eugenio Aguglia
Affiliation:
Keywords: Depression, mood stabilizers, pruritus, side effects, skin disorders, topiramate.
Abstract: A 41-year-old woman with Major Depressive Disorder-Recurrent was treated with topiramate at 150 mg/day. After this administration, she developed intense pruritus and skin lesions due to scratching. Consequently, she was weaned off topiramate and the lesions regressed. Pruritus and cutaneous lesions are extremely rare side effects of topiramate, so we report an interesting case of skin reaction to this drug.
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Cite this article as:
Signorelli S. Maria, Cinconze Maria, Nasca R. Maria, Marino Monica, Martinotti Giovanni, Di Giannantonio Massimo and Aguglia Eugenio, Can Topiramate Induce Pruritus? A Case Report and Review of Literature, CNS & Neurological Disorders - Drug Targets 2015; 14 (3) . https://dx.doi.org/10.2174/1871527314666150225123827
DOI https://dx.doi.org/10.2174/1871527314666150225123827 |
Print ISSN 1871-5273 |
Publisher Name Bentham Science Publisher |
Online ISSN 1996-3181 |
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