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Current Organic Chemistry


ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Palladium-Catalyzed Reactions on 1,2-Diazines

Author(s): Caroline Meyers, Peter Matyus, Pal Tapolcsanyi and Bert U.W. Maes

Volume 10, Issue 3, 2006

Page: [377 - 417] Pages: 41

DOI: 10.2174/138527206775473841

Price: $65


In this report, we review the C- and N-functionalization of the pyridazine nucleus via palladium-catalyzed reactions (Suzuki, Stille, Sonogashira, carbonylation, Heck, Buchwald-Hartwig) in which carbon atoms of the pyridazine nucleus are involved. The efficient use of these reactions in synthetic strategies to build up polycyclic 1,2-diazines is also included.

Keywords: pyridazine nucleus, Negishi Reaction, Organometallic reagents, Chloropyridazines, brominated bicyclic fused system

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