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Combinatorial Chemistry & High Throughput Screening


ISSN (Print): 1386-2073
ISSN (Online): 1875-5402

ZnO-Nanorods as the Catalyst for the Synthesis of 1,3-Thiazole Derivatives via Multicomponent Reactions

Author(s): Rahimeh Hajinasiri, Zinatossadat Hossaini and Fatemeh Sheikholeslami-Farahani

Volume 18 , Issue 1 , 2015

Page: [42 - 47] Pages: 6

DOI: 10.2174/1386207317666141203123133

Price: $65


Environmentally method for the synthesis of 1,3-thiazole has been achieved by multicomponent reactions of primary amines, isothiosyanates and alkyl bromides under solvent-free conditions using nanorod ZnO structures as catalyst. These reactions were not performed without catalyst. The catalyst showed significant reusable activity.

Keywords: Alkyl bromides, isothiosyanates, multicomponent reactions, Nanorod ZnO, primary amines.

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