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Current Green Chemistry


ISSN (Print): 2213-3461
ISSN (Online): 2213-347X

Progress in Copper-Mediated Functionalization of Unactivated C-H Bonds Assisted by Directing Groups

Author(s): Hu Jia-Lei, Li Jie and Zhou Yi-Feng

Volume 2 , Issue 2 , 2015

Page: [170 - 191] Pages: 22

DOI: 10.2174/2213346101666141202234329

Price: $65


The strategy of employing directing groups in C-H activation appears to be a big success in today's chemical synthesis due to its high efficiency and environmental friendly process. As various methodologies have been developed by using copper, this widespread and cheap catalyst has also played an important role in C-H activation. This review focuses on copper involved C-H activation assisted by directing groups developed in recent years, with the aim of providing a complementary to existing reviews.

Keywords: Carbon-carbon bonds, carbon-heteroatom bonds, copper, directing groups, functionalization, green chemistry, unactivated C-H bonds.

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