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Cardiovascular & Hematological Agents in Medicinal Chemistry


ISSN (Print): 1871-5257
ISSN (Online): 1875-6182

Safety and Efficacy of Novel Oral Anticoagulants: A Comparison to Vitamin K Antagonists

Author(s): Antonios Katsianis, Emmanouil Petrou, Anna Kostopoulou and George Theodorakis

Volume 12 , Issue 1 , 2014

Page: [9 - 13] Pages: 5

DOI: 10.2174/187152571201141201092129

Price: $65


Novel oral anticoagulants (NOACs) have been developed as alternatives for vitamin K antagonists (VKAs) for the prevention of thromboembolic events in patients with a variety of medical conditions. In this review, we summarize the current data on NOACs safety and efficacy compared to VKAs and in specific patients’ groups including heart valve replacement, venous thromboembolism, advanced renal failure and the elderly.

Keywords: Efficacy, novel oral anticoagulants, safety, vitamin K antagonists.

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