Safety and Efficacy of Novel Oral Anticoagulants: A Comparison to Vitamin K Antagonists

Title:Safety and Efficacy of Novel Oral Anticoagulants: A Comparison to Vitamin K Antagonists

Volume: 12 Issue: 1

Author(s): Antonios Katsianis, Emmanouil Petrou, Anna Kostopoulou and George Theodorakis

Affiliation:

• Division of Cardiology, Onassis Cardiac Surgery Center, 356 Syggrou Ave., GR-17674, Athens, Greece.,Greece

Keywords: Efficacy, novel oral anticoagulants, safety, vitamin K antagonists.

Abstract: Novel oral anticoagulants (NOACs) have been developed as alternatives for vitamin K antagonists (VKAs) for the prevention of thromboembolic events in patients with a variety of medical conditions. In this review, we summarize the current data on NOACs safety and efficacy compared to VKAs and in specific patients’ groups including heart valve replacement, venous thromboembolism, advanced renal failure and the elderly.

Cite this article as:

Katsianis Antonios, Petrou Emmanouil, Kostopoulou Anna and Theodorakis George, Safety and Efficacy of Novel Oral Anticoagulants: A Comparison to Vitamin K Antagonists, Cardiovascular & Hematological Agents in Medicinal Chemistry 2014; 12(1) . https://dx.doi.org/10.2174/187152571201141201092129