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Current Organocatalysis


ISSN (Print): 2213-3372
ISSN (Online): 2213-3380

Chiral Bifunctional Ferrocenylphosphines as New Catalysts for aza- Morita-Baylis-Hillman Reactions of N-Sulfonated Imines with Methyl Vinyl Ketone

Author(s): Haiwen Hu, Qian Tang, Aiping Tu and Weihui Zhong

Volume 2 , Issue 1 , 2015

Page: [58 - 63] Pages: 6

DOI: 10.2174/2213337201666141111225445

Price: $65


A series of new chiral bifunctional Ferrocenylphosphines was designed, synthesized and applied for the asymmetric aza-Morita-Baylis-Hillman reaction of N-sulfonated imines with methyl vinyl ketone (MVK). The reaction proceeded under mild conditions to afford the desired aza-MBH adducts in moderate to high yields with up to 56% ee value.

Keywords: aza-MBH adducts, aza-Morita-Baylis-Hillman reaction, chiral bifunctional ferrocenylphosphines, organocatalyst.

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