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Current Organocatalysis

Editor-in-Chief

ISSN (Print): 2213-3372
ISSN (Online): 2213-3380

Dearomatization Strategies of Heteroaromatic Compounds

Author(s): Gunasekar Ramachandran and Kulathu Iyer Sathiyanarayanan

Volume 2 , Issue 1 , 2015

Page: [14 - 26] Pages: 13

DOI: 10.2174/2213337201666141110222735

Price: $65

Abstract

Dearomatization strategies of heteroaromatic compounds such as benzofurans, indoles, thiophenes, pyridines, and other heteroaromatic compounds afford the most efficient protocol for the synthesis of highly bioactive molecules, natural products and commercially available drugs. The use of these strategies has been significantly increased, which has fascinated several research groups as the dearomatization strategies of heteroaromatic compounds at C-2 & C-3 substitution leads to formation of numerous drug-like molecules. The recent developments in dearomatization strategies involving at C-2 & C-3 positions of various heteroaromatic compounds is discussed in this review.

Keywords: Benzofurans, dearomatization, furans and indoles, heteroaromatic.

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