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Current Alzheimer Research

Editor-in-Chief

ISSN (Print): 1567-2050
ISSN (Online): 1875-5828

Platelets as Potential Link Between Diabetes and Alzheimer's Disease

Author(s): Voahanginirina Randriamboavonjy, Kateryna Sopova, Konstantinos Stellos and Christoph Laske

Volume 11 , Issue 9 , 2014

Page: [862 - 868] Pages: 7

DOI: 10.2174/156720501109141013115258

Price: $65

Abstract

Diabetes is a well-known risk factor for Alzheimer`s disease (AD) development in the elderly. The molecular link between diabetes and AD is still not completely understood. Recent evidence suggests that platelet activation observed in diabetes may contribute to AD development. The present review summarizes the common molecular mechanisms involved in the pathophysiology of diabetes and AD and suggests novel therapeutic targets for prevention of the onset or slowing the progression of this disease.

Keywords: Alzheimer's disease, diabetes, platelets, vascular dementia.


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