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Current Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

Syntheses of Hydroxylated Cyclic β-Amino Acid Derivatives

Author(s): Marta Palko, Lorand Kiss and Ferenc Fulop

Volume 12, Issue 26, 2005

Page: [3063 - 3083] Pages: 21

DOI: 10.2174/092986705774933443

Price: $65

Abstract

This review is intended to give a short summary of the developments in the field of natural and synthetic alicyclic and heterocyclic hydroxylated β-amino acids and to focus on the main strategies that have been reported for their synthesis. Given the medicinal and biological significance of the hydroxylated β-amino acids, an increasing volume of research is currently being directed toward regio-, stereo- and enantioselective access to this class of compounds.

Keywords: β-amino acids, peptides, asymmetric synthesis, selective functionalization


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