摘要
恶性黑色素瘤是导致年轻人患癌症和癌症死亡的最普遍的原因之一。直到数年前,极少的药物证明在癌细胞转移治疗方面有效。但是,近些年,转移性恶性黑色素瘤的治疗采用了有效的疗法例如免疫疗法,络氨酸激酶抑制剂的使用和其他抑制细胞生长的化合物,像纳米粒子。这篇综述旨在提出一种根据化学性质来区分纳米粒子不同类型的标准,并更新纳米粒子的临床研究和它们在黑色素瘤治疗领域的应用。
关键词: 癌症,分类,黑素瘤,紫杉醇,纳米粒子
Current Medicinal Chemistry
Title:Nanoparticles in Melanoma
Volume: 21 Issue: 32
Author(s): M.A. Berciano-Guerrero, A. Montesa-Pino, G. Castaneda-Penalvo, L. Munoz-Fernandez and J. Rodriguez-Flores
Affiliation:
关键词: 癌症,分类,黑素瘤,紫杉醇,纳米粒子
摘要: Malignant melanoma is one of the most common causes of cancer and cancer deaths in young people. Until few years ago, scarce drugs have proven efficacy in metastatic setting. However, in the recent years, the treatment of metastatic malignant melanoma has undergone the incorporation of effective treatment such as immunotherapy, the use of tyrosine kinase inhibitors and the emergence of other cytostatic compounds, like the nanoparticles. This review aims to propose a standardization to classify the different types of nanoparticles, according to chemical aspects, and update the clinical research with nanoparticles and their use in melanoma field.
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Berciano-Guerrero M.A., Montesa-Pino A., Castaneda-Penalvo G., Munoz-Fernandez L. and Rodriguez-Flores J., Nanoparticles in Melanoma, Current Medicinal Chemistry 2014; 21 (32) . https://dx.doi.org/10.2174/0929867321666140716092512
DOI https://dx.doi.org/10.2174/0929867321666140716092512 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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