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Current Chromatography


ISSN (Print): 2213-2406
ISSN (Online): 2213-2414

Recent Trends in Chiral Separations by Nano Liquid Chromatography and Nano Capillary Electrophoresis

Author(s): Imran Ali, Zeid A. Al-Othman, Abdulrahman Al-Warthan and Hassan Y. Aboul-Enein

Volume 1, Issue 2, 2014

Page: [81 - 89] Pages: 9

DOI: 10.2174/2213240601666140301001948


Chiral separation at nano scale is gaining importance in drugs development, proteomic, genomic and environmental sciences. Generally, traces of drugs are found in our body for several weeks. These cannot be detected by conventional analytical techniques. The present article discusses the advances in chiral resolution at nano scale using nano liquid chromatography (NLC) and nano capillary electrophoresis (NCE). The instrumentation, chiral selectors, mechanisms of chiral recognition and future challenges and prospectives have been discussed.

Keywords: Challenges and prospectives, chiral recognition mechanisms, chiral separations, nano capillary electrophoresis (NCE), nano liquid chromatography (NLC).

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