Abstract
In this review authors address colostrum proteins implications in different domestic ruminant species. The colostrogenesis process and how different factors, such as litter size or nutrition during gestation can alter the different components concentrations in colostrum are also reviewed. The different colostrum fractions will be described, focusing on high and low abundant proteins. This review describes the major function of such proteins and their role on the passive immune transfer and nutrition in the newborn animal. It will be also performed a comprehensive review on different techniques and commercial kits available for high abundant protein depletion in colostrum. We will finally focus on how proteomics has been used to address this issue and how it can contribute to the major questions about colostrum associated immunology.
Keywords: Colostrum, depletion, immune system, low abundant proteins, proteomics.
Current Protein & Peptide Science
Title:The Colostrum Proteome, Ruminant Nutrition and Immunity: A Review
Volume: 15 Issue: 1
Author(s): Lorenzo E. Hernandez-Castellano, Andre M. Almeida, Noemi Castro and Anastasio Arguello
Affiliation:
Keywords: Colostrum, depletion, immune system, low abundant proteins, proteomics.
Abstract: In this review authors address colostrum proteins implications in different domestic ruminant species. The colostrogenesis process and how different factors, such as litter size or nutrition during gestation can alter the different components concentrations in colostrum are also reviewed. The different colostrum fractions will be described, focusing on high and low abundant proteins. This review describes the major function of such proteins and their role on the passive immune transfer and nutrition in the newborn animal. It will be also performed a comprehensive review on different techniques and commercial kits available for high abundant protein depletion in colostrum. We will finally focus on how proteomics has been used to address this issue and how it can contribute to the major questions about colostrum associated immunology.
Export Options
About this article
Cite this article as:
Hernandez-Castellano E. Lorenzo, Almeida M. Andre, Castro Noemi and Arguello Anastasio, The Colostrum Proteome, Ruminant Nutrition and Immunity: A Review, Current Protein & Peptide Science 2014; 15 (1) . https://dx.doi.org/10.2174/1389203715666140221124622
DOI https://dx.doi.org/10.2174/1389203715666140221124622 |
Print ISSN 1389-2037 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5550 |
Call for Papers in Thematic Issues
Advancements in Proteomic and Peptidomic Approaches in Cancer Immunotherapy: Unveiling the Immune Microenvironment
The scope of this thematic issue centers on the integration of proteomic and peptidomic technologies into the field of cancer immunotherapy, with a particular emphasis on exploring the tumor immune microenvironment. This issue aims to gather contributions that illustrate the application of these advanced methodologies in unveiling the complex interplay ...read more
Artificial Intelligence for Protein Research
Protein research, essential for understanding biological processes and creating therapeutics, faces challenges due to the intricate nature of protein structures and functions. Traditional methods are limited in exploring the vast protein sequence space efficiently. Artificial intelligence (AI) and machine learning (ML) offer promising solutions by improving predictions and speeding up ...read more
Nutrition and Metabolism in Musculoskeletal Diseases
The musculoskeletal system consists mainly of cartilage, bone, muscles, tendons, connective tissue and ligaments. Balanced metabolism is of vital importance for the homeostasis of the musculoskeletal system. A series of musculoskeletal diseases (for example, sarcopenia, osteoporosis) are resulted from the dysregulated metabolism of the musculoskeletal system. Furthermore, metabolic diseases (such ...read more
Protein Folding, Aggregation and Liquid-Liquid Phase Separation
Protein folding, misfolding and aggregation remain one of the main problems of interdisciplinary science not only because many questions are still open, but also because they are important from the point of view of practical application. Protein aggregation and formation of fibrillar structures, for example, is a hallmark of a ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Copper Complexes of 8-Aminoquinoline and Uracils as Novel Aromatase Inhibitors
Letters in Drug Design & Discovery Spectroscopic and Theoretical Approaches for the Determination of Heparin Saccharide Structure and the Study of Protein-Glycosaminoglycan Complexes in Solution
Current Medicinal Chemistry The Role of NAD+ Dependent Histone Deacetylases (sirtuins) in Ageing
Current Drug Targets <i>In Silico</i> Molecular Interaction Studies of Chitosan Polymer with Aromatase Inhibitor: Leads to Letrozole Nanoparticles for the Treatment of Breast Cancer
Anti-Cancer Agents in Medicinal Chemistry Erythropoietin and Oxidative Stress
Current Neurovascular Research Presystemic Metabolism of Orally Administered Peptide Drugs and Strategies to Overcome It
Current Drug Metabolism HDL Therapy: Two Kinds of Right?
Current Pharmaceutical Design Modifications of Isoalantolactone Leading to Effective Anti-bacterial and Anti-viral Compounds
Letters in Drug Design & Discovery Discovery of Novel Plant Peptides as Strong Inhibitors of Metalloproteinases
Protein & Peptide Letters Sialic Acid and the Central Nervous System: Perspectives on Biological Functions, Detection, Imaging Methods and Manipulation
CNS & Neurological Disorders - Drug Targets The Oxygen Therapy
Current Medicinal Chemistry Structural Biology of Antimicrobial Peptides by NMR Spectroscopy
Current Organic Chemistry Thalidomide: An Overview of its Pharmacological Mechanisms of Action
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry Peptoids: Bio-Inspired Polymers as Potential Pharmaceuticals
Current Pharmaceutical Design Role of Genetic Factors in the Pathogenesis of Radial Deficiencies in Humans
Current Genomics Advances in Antioxidant Potential of Natural Alkaloids
Current Bioactive Compounds Chemistry and Pharmacology of Angiotensin-Converting Enzyme Inhibitors
Current Pharmaceutical Design Application of Molecular Imaging Technologies in Antitumor Drug Development and Therapy
Current Pharmaceutical Design Comparative Study of Two Different Speciation Methods for the Determination of Hexavalent Chromium in Water Samples Using Electrothermal Atomic Absorption Spectrometry
Current Analytical Chemistry Inhibition of Sulfotransferases by Xenobiotics
Current Drug Metabolism