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Current Medicinal Chemistry


ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

Peptides-Staple Method Development and Its Application in Cancer Therapy

Author(s): Q.Z. Zhang, Y. Tian, Y.Z. Lao and Z.-G. Li

Volume 21 , Issue 21 , 2014

Page: [2438 - 2452] Pages: 15

DOI: 10.2174/0929867321666140205130835

Price: $65


α-Helixes are important structural motifs of protein three dimension structures and are largely involved in protein- protein interactions. This review covers the recent advances of the peptide stabilizing methodologies and introduces their applications in cancer research.

Keywords: Cancer therapy, protein-protein interaction, stapled peptide, α-helix.

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