Abstract
In the recent years many advances have been achieved in the field of the treatment of lung cancer; with the development of novel therapeutic pathways due to the knowledge of oncologic drivers involved in the carcinogenesis of the lung, as well as the involvement of new radiotherapic and surgical techniques. Nevertheless, the standard treatment for elderly is still debated, mainly because of an underrepresentation of elderly patients in clinical trials. Herein we try to summarize the main guidelines for the treatment of lung cancer, with particular attention for the elderly patients, what we know and what has changed.
Keywords: Lung Cancer, non-small cell lung cancer, small cell lung cancer, elderly patients, surgery, radiotherapy, chemotherapy, adjuvant treatment, locally advanced nsclc, metastatic lung cancer, clinical trials, multimodality treatment, cutoff point, geriatric oncology, comprehensive geriatric assessment.
Anti-Cancer Agents in Medicinal Chemistry
Title:Treatment of Elderly Patients Affected by Lung Cancer: Why to Treat, when to Treat and what we Know
Volume: 13 Issue: 9
Author(s): Alessandra Bearz, Massimiliano Berretta, Arben Lleshi, Eleonora Berto and Umberto Tirelli
Affiliation:
Keywords: Lung Cancer, non-small cell lung cancer, small cell lung cancer, elderly patients, surgery, radiotherapy, chemotherapy, adjuvant treatment, locally advanced nsclc, metastatic lung cancer, clinical trials, multimodality treatment, cutoff point, geriatric oncology, comprehensive geriatric assessment.
Abstract: In the recent years many advances have been achieved in the field of the treatment of lung cancer; with the development of novel therapeutic pathways due to the knowledge of oncologic drivers involved in the carcinogenesis of the lung, as well as the involvement of new radiotherapic and surgical techniques. Nevertheless, the standard treatment for elderly is still debated, mainly because of an underrepresentation of elderly patients in clinical trials. Herein we try to summarize the main guidelines for the treatment of lung cancer, with particular attention for the elderly patients, what we know and what has changed.
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Cite this article as:
Bearz Alessandra, Berretta Massimiliano, Lleshi Arben, Berto Eleonora and Tirelli Umberto, Treatment of Elderly Patients Affected by Lung Cancer: Why to Treat, when to Treat and what we Know, Anti-Cancer Agents in Medicinal Chemistry 2013; 13 (9) . https://dx.doi.org/10.2174/18715206113136660353
DOI https://dx.doi.org/10.2174/18715206113136660353 |
Print ISSN 1871-5206 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5992 |
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