Abstract
For several decades, interest in pyrrole derivatives increased due to their pharmaceutical importance, such as antimicrobial, anti-inflammatory, analgesic, anti-tumor, anti-epileptic, anti-viral, anti-hypertensive, and anti-diabetic agents. These huge therapeutic applications have motivated new efforts in searching for novel derivatives with improved biological activity and diverse applications in pharmaceutical industry. Motivated by the importance of this system, and in continuation of our research efforts, we have tried to highlight aspects reported on the chemistry and biological activity of pyrrole and its fused derivatives during the past years (till 2012).
Keywords: Pyrrole, fused pyrrole, pyrrolopyrimidine, synthesis, biological activities and drugs.
Mini-Reviews in Organic Chemistry
Title:Pyrroles and Fused Pyrroles: Synthesis and Therapeutic Activities
Volume: 11 Issue: 4
Author(s): Mosaad S. Mohamed and Samar S. Fathallah
Affiliation:
Keywords: Pyrrole, fused pyrrole, pyrrolopyrimidine, synthesis, biological activities and drugs.
Abstract: For several decades, interest in pyrrole derivatives increased due to their pharmaceutical importance, such as antimicrobial, anti-inflammatory, analgesic, anti-tumor, anti-epileptic, anti-viral, anti-hypertensive, and anti-diabetic agents. These huge therapeutic applications have motivated new efforts in searching for novel derivatives with improved biological activity and diverse applications in pharmaceutical industry. Motivated by the importance of this system, and in continuation of our research efforts, we have tried to highlight aspects reported on the chemistry and biological activity of pyrrole and its fused derivatives during the past years (till 2012).
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Cite this article as:
Mohamed S. Mosaad and Fathallah S. Samar, Pyrroles and Fused Pyrroles: Synthesis and Therapeutic Activities, Mini-Reviews in Organic Chemistry 2014; 11 (4) . https://dx.doi.org/10.2174/1570193X113106660018
DOI https://dx.doi.org/10.2174/1570193X113106660018 |
Print ISSN 1570-193X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6298 |
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