Abstract
In the present work, magnetic nanoparticles coated with silica or ORMOSIL are prepared in a two step process. In the first step, SPIONs with 6 nm average diameter are produced by a reduction-precipitation process conducted in air and in the second one, SPIONs were used as seeds for silica/ORMOSIL growth (below 30 nm), in situ by a modified Stöber sol-gel method. SPIONs and silica/ ORMOSIL magnetic core-shell nanostructures were characterized by X-Ray diffraction (XRD), Fourier transformed infrared (FTIR) spectroscopy, transmission electron microscopy (TEM), Mössbauer spectroscopy and SQUID magnetometry. TEM observations of SPIONs and silica/ORMOSIL SPIONs allow determining size and shape. FTIR allows determining silica/ORMOSIL structural fingerprints. X-ray and Mössbauer spectroscopy allow determining the magnetite/maghemite ratio, discussed as a nanosized constrained. SPIONs and silica/ORMOSIL SPIONs show superparamagnetic properties making them appropriated to biomedical applications.
Keywords: Superparamagnetic iron oxide nanoparticles, SPIONs, silica/ORMOSIL coating, sol-gel, core-shell nanostructures.
Current Nanoscience
Title:Silica/Ormosil SPIONs for Biomedical Applications
Volume: 9 Issue: 5
Author(s): M. C. Gonçalves, L. M. Fortes, A. R. Pimenta, J. C.G. Pereira, R. M. Almeida, M. D. Carvalho, L. P. Ferreira, M. M. Cruz and M. Godinho
Affiliation:
Keywords: Superparamagnetic iron oxide nanoparticles, SPIONs, silica/ORMOSIL coating, sol-gel, core-shell nanostructures.
Abstract: In the present work, magnetic nanoparticles coated with silica or ORMOSIL are prepared in a two step process. In the first step, SPIONs with 6 nm average diameter are produced by a reduction-precipitation process conducted in air and in the second one, SPIONs were used as seeds for silica/ORMOSIL growth (below 30 nm), in situ by a modified Stöber sol-gel method. SPIONs and silica/ ORMOSIL magnetic core-shell nanostructures were characterized by X-Ray diffraction (XRD), Fourier transformed infrared (FTIR) spectroscopy, transmission electron microscopy (TEM), Mössbauer spectroscopy and SQUID magnetometry. TEM observations of SPIONs and silica/ORMOSIL SPIONs allow determining size and shape. FTIR allows determining silica/ORMOSIL structural fingerprints. X-ray and Mössbauer spectroscopy allow determining the magnetite/maghemite ratio, discussed as a nanosized constrained. SPIONs and silica/ORMOSIL SPIONs show superparamagnetic properties making them appropriated to biomedical applications.
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Cite this article as:
Gonçalves C. M., Fortes M. L., Pimenta R. A., Pereira C.G. J., Almeida M. R., Carvalho D. M., Ferreira P. L., Cruz M. M. and Godinho M., Silica/Ormosil SPIONs for Biomedical Applications, Current Nanoscience 2013; 9 (5) . https://dx.doi.org/10.2174/15734137113099990004
DOI https://dx.doi.org/10.2174/15734137113099990004 |
Print ISSN 1573-4137 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6786 |
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