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Current Organocatalysis

Editor-in-Chief

ISSN (Print): 2213-3372
ISSN (Online): 2213-3380

Nitrogen Bound Polymers as Heterogeneous Basic Catalysts for Diastereoselective Henry Reaction in Aqueous Medium

Author(s): Parishmita Sarma, Pinky Gogoi and Ruli Borah

Volume 1 , Issue 1 , 2014

Page: [40 - 44] Pages: 5

DOI: 10.2174/221333720101140529112354

Abstract

Poly(4-vinylpyridine) (P4VP) has been found as an efficient recyclable heterogeneous Lewis base catalyst for the diastereoselective synthesis of syn-2-nitroalkanols in aqueous medium. The 1H NMR and 13C NMR spectra of 2- nitroalkanols are utilized for determining the ratios of syn/anti stereoisomers. This protocol provides a simple greener path for the synthesis of 2-nitroalcohols in aqueous medium at ambient condition with high yields.

Keywords: Aqueous medium, ambient temperature, cyclic transition state mechanism, diastereoselective, environmentally benign, heterogeneous catalyst, Henry reaction, high yields, syn-2-Nitroalkanols, Poly-4-vinylpyridine, reusable catalyst.

Graphical Abstract

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