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Recent Patents on DNA & Gene Sequences


ISSN (Print): 1872-2156
ISSN (Online): 2212-3431

Patented Biotechnological Applications of Serpin: an Update

Author(s): Nadia Gaci, Dragana Dobrijevic, Samira Boudebbouze, Bouziane Moumen, Emmanuelle Maguin and Moez Rhimi

Volume 7 , Issue 2 , 2013

Page: [137 - 143] Pages: 7

DOI: 10.2174/1872215611307020008

Price: $65


The Serine Protease Inhibitors (Serpins) have been a focus of research by biomedical industries due to their critical role in human health. The use of serpin in the treatment of many diseases was widely investigated through the identification of new genes encoding these proteins in all kingdoms of life. The characterization of these genes revealed that they encoded proteins having low sequence homologies. Future developments are focusing not only on the protease inhibition activity, but also on the other effects due to the interactions of serpins with other components such as hormone transport. Here we give a concise overview of the most recent patents that have been reported in this field of research.

Keywords: Serpin, biotechnological applications, health, blood clotting, cancer, anti-viral, inflammation.

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