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Inflammation & Allergy - Drug Targets (Discontinued)

Editor-in-Chief

ISSN (Print): 1871-5281
ISSN (Online): 2212-4055

Vitamin D and Sepsis: From Associations to Causal Connections

Author(s): Jordan A. Kempker and Greg S. Martin

Volume 12 , Issue 4 , 2013

Page: [246 - 252] Pages: 7

DOI: 10.2174/18715281113129990048

Price: $65

Abstract

The physiological roles of vitamin D in the functioning of the immune and inflammatory systems have been the subject of intense research over the past decade and have stimulated interest in the connections between this steroid hormone and sepsis. While the science directly examining the relationship between sepsis and vitamin D is still emerging, many inferences can be made from current literature from various scientific disciplines looking at the seasonal, geographical and racial patterns of infections and vitamin D deficiency. This review will explore these associations, drawing from the fields of ecology, epidemiology and clinical research and describe the potential causal relationships implicated by the basic sciences.

Keywords: Critical illness, ecology, epidemiology, immunology, immunonutrition, infection, nutrition, sepsis, vitamin D.


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