Drug-Delivery Systems of Green Tea Catechins for Improved Stability and Bioavailability

Title:Drug-Delivery Systems of Green Tea Catechins for Improved Stability and Bioavailability

Volume: 20 Issue: 37

Author(s): C. F. Rodrigues, K. Ascenção, F. A.M. Silva, B. Sarmento, M. B.P.P. Oliveira and J. C. Andrade

Affiliation:

Keywords: Antioxidant, drug delivery, epigallocatechin-3-gallate, green tea polyphenols, catechins, EGCG.

Abstract: Numerous studies in humans, animal models and cell lines have suggested the potential benefits from the consumption of green tea polyphenols, including prevention of cancer and heart diseases. However these potential effects have been strongly limited by green tea catechins low bioavailability, which hinders the development of therapeutic applications. In this review formulations that are being proposed for delivery of green tea catechins are discussed. New delivery systems are presented as valid alternatives to overcome the limitations such as green tea catechins poor stability or intestinal absorption.

Cite this article as:

Rodrigues F. C., Ascenção K., Silva A.M. F., Sarmento B., Oliveira B.P.P. M. and Andrade C. J., Drug-Delivery Systems of Green Tea Catechins for Improved Stability and Bioavailability, Current Medicinal Chemistry 2013; 20(37) . https://dx.doi.org/10.2174/09298673113209990158