Abstract
Skin and gut represent physical and immunological barriers between internal and external environment. Some affections involving the intestine, such as celiac disease, are reported to be associated with several different cutaneous diseases, like dermatitis herpetiforme or psoriasis. This could be better explained if gut and skin are taken as complex structures that share physio-pathological and immunological aspects.
As a proof, we present the case of a woman affected by celiac disease who presented with three different skin manifestations strongly related in terms of onset, response to therapy and improvement during gluten-free diet.
Keywords: Celiac disease, psoriasis, GWAS, gluten-free diet, inflammatory bowel diseases, T helper 1.
Current Pharmaceutical Design
Title:Skin Manifestations in Course of Celiac Disease: Case Report and Review of the Literature
Volume: 20 Issue: 7
Author(s): Skroza Nevena, Proietti Ilaria, Bernardini Nicoletta, La Viola Giorgio, Mancini Maria Teresa, Nicolucci Francesca, Pampena Riccardo, Tolino Ersilia, Zuber Sara and Potenza Concetta
Affiliation:
Keywords: Celiac disease, psoriasis, GWAS, gluten-free diet, inflammatory bowel diseases, T helper 1.
Abstract: Skin and gut represent physical and immunological barriers between internal and external environment. Some affections involving the intestine, such as celiac disease, are reported to be associated with several different cutaneous diseases, like dermatitis herpetiforme or psoriasis. This could be better explained if gut and skin are taken as complex structures that share physio-pathological and immunological aspects.
As a proof, we present the case of a woman affected by celiac disease who presented with three different skin manifestations strongly related in terms of onset, response to therapy and improvement during gluten-free diet.
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Cite this article as:
Nevena Skroza, Ilaria Proietti, Nicoletta Bernardini, Giorgio Viola La, Teresa Maria Mancini, Francesca Nicolucci, Riccardo Pampena, Ersilia Tolino, Sara Zuber and Concetta Potenza, Skin Manifestations in Course of Celiac Disease: Case Report and Review of the Literature, Current Pharmaceutical Design 2014; 20 (7) . https://dx.doi.org/10.2174/13816128113199990455
DOI https://dx.doi.org/10.2174/13816128113199990455 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
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