Abstract
Benzimidazoles exhibit a broad range of biological activities. Several benzimidazoles are used in therapy such as albendazole, mebendazole, flubendazole, fenbendazole, omeprazole, lansoprazole,clofazimine. Benzimidazole derivatives play a vital role in the biological field such as antimicrobial, antiviral, antidiabetic, antiulcer and anticancer activities. The present review highlights the recently synthesized benzimidazoles possessing important potential biological activities as chemotherapeutic agents.
Keywords: Antimicrobial, anti-ulcer benzimidazole, chemotherapeutic agents.
Current Drug Therapy
Title:Benzimidazole Derivatives as Potential Chemotherapeutic Agents
Volume: 8 Issue: 1
Author(s): Ahmed A. El Rashedy and Hassan Y. Aboul-Enein
Affiliation:
Keywords: Antimicrobial, anti-ulcer benzimidazole, chemotherapeutic agents.
Abstract: Benzimidazoles exhibit a broad range of biological activities. Several benzimidazoles are used in therapy such as albendazole, mebendazole, flubendazole, fenbendazole, omeprazole, lansoprazole,clofazimine. Benzimidazole derivatives play a vital role in the biological field such as antimicrobial, antiviral, antidiabetic, antiulcer and anticancer activities. The present review highlights the recently synthesized benzimidazoles possessing important potential biological activities as chemotherapeutic agents.
Export Options
About this article
Cite this article as:
Rashedy A. El Ahmed and Aboul-Enein Y. Hassan, Benzimidazole Derivatives as Potential Chemotherapeutic Agents, Current Drug Therapy 2013; 8 (1) . https://dx.doi.org/10.2174/1574885511308010001
DOI https://dx.doi.org/10.2174/1574885511308010001 |
Print ISSN 1574-8855 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3903 |
Call for Papers in Thematic Issues
Novel Therapeutic Approaches and Biomarkers for Chronic Kidney Disease (CKD)
The thematic issue on "Novel Therapeutic Approaches and Biomarkers for CKD" aims to provide a comprehensive exploration of cutting-edge strategies for the management of chronic kidney disease (CKD). This issue will delve into emerging therapeutic targets, focusing on critical aspects such as podocyte injury, endothelial dysfunction, and tubulointerstitial fibrosis, which ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
The Health-promoting Potential of Edible Mushroom Proteins
Current Pharmaceutical Design Insights on Antimicrobial Resistance, Biofilms and the Use of Phytochemicals as New Antimicrobial Agents
Current Medicinal Chemistry The Rationale and Development of New Drugs to Treat HIV Infection
Medicinal Chemistry Independent Component Analysis Applied to Pharmacological Magnetic Resonance Imaging (phMRI): New Insights Into the Functional Networks Underlying Panic Attacks as Induced by CCK-4
Current Pharmaceutical Design Thapsigargin, Origin, Chemistry, Structure-Activity Relationships and Prodrug Development
Current Pharmaceutical Design Successful Screening of Large Encoded Combinatorial Libraries Leading to the Discovery of Novel p38 MAP Kinase Inhibitors
Combinatorial Chemistry & High Throughput Screening Modulation of Neutrophil Function by Hormones
Current Immunology Reviews (Discontinued) Translocator Protein (TSPO) and Neurosteroids: Implications in Psychiatric Disorders
Current Molecular Medicine Lanthanides as Anticancer Agents
Current Medicinal Chemistry - Anti-Cancer Agents Chemical Space of FLT3 Inhibitors as Potential Anti-AML Drugs
Recent Patents on Anti-Cancer Drug Discovery Epigenetic Modulators as Treatment Alternative to Diverse Types of Cancer
Current Medicinal Chemistry Synthesis of New 2-(N-Arylsulfonylindol-3-yl)-3-aryl-1,3-thiazolidin-4-ones as HIV-1 Inhibitors In Vitro
Letters in Drug Design & Discovery Design, Synthesis and Biological Evaluation of 2, 4, 5-Triphenylimidazole Derivatives with Preliminary SAR
Letters in Drug Design & Discovery Thiazoles and Thiazolidinones as Antioxidants
Current Medicinal Chemistry Efficient Synthesis of Fused Pyrimidine Derivatives with Biological Activity via Aza-Wittig Reaction
Current Organic Synthesis Recent Developments in Group I Metabotropic Glutamate Receptor Allosteric Modulators for the Treatment of Psychiatric and Neurological Disorders (2014-May 2015)
Current Topics in Medicinal Chemistry Pro-apoptotic Activity of BH3-only Proteins and BH3 Mimetics: from Theory to Potential Cancer Therapy
Anti-Cancer Agents in Medicinal Chemistry Fragment Based Drug Design: From Experimental to Computational Approaches
Current Medicinal Chemistry Structure, Chemistry and Pharmacology of Naphthoflavones
Mini-Reviews in Medicinal Chemistry The Chemistry and Biological Effects of Thioflavones
Mini-Reviews in Medicinal Chemistry