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Letters in Organic Chemistry


ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Rapid and Efficient Synthesis of N-alkylbenzamides Under Microwave Irradiation

Author(s): Jan K. Cermak, Karel Kolar and Vladimir Cirkva

Volume 10, Issue 2, 2013

Page: [126 - 130] Pages: 5

DOI: 10.2174/1570178611310020011


The microwave-assisted synthesis of N-alkylbenzamides from benzoic acid and primary aliphatic amines has been developed under solvent-free conditions. The different solid catalysts have been investigated. The suggested synthesis is environmentally friendly and excellent yields (97 - 99 %) have been reached.

Keywords: Amino-de-hydroxylation, heterogenous catalyst, microporous materials, microwave assisted synthesis, Nalkylbenzamides, solvent-free reaction

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