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Infectious Disorders - Drug Targets


ISSN (Print): 1871-5265
ISSN (Online): 2212-3989

Biology of Circulating Nucleic Acids and Possible Roles in Diagnosis and Treatment in Diabetes and Cancer

Author(s): Peter B. Gahan

Volume 12, Issue 5, 2012

Page: [360 - 370] Pages: 11

DOI: 10.2174/187152612804142224

Price: $65


The presence of DNA and RNA circulating in human plasma and serum is described. The possible sources of the DNA/RNA in blood, their ability to enter other cells and to express in the recipient cells are discussed and the relationship with metastases considered. The possible role(s) of the DNA/RNA in clinical diagnosis, in monitoring treatment and in prognosis are considered for diabetes and oncology.

Keywords: Circulating DNA/RNA, plasma/serum, diabetes, cancer, diagnosis, nucleic acid uptake/expression, recipient cells, human plasma, human blood, severe sepsis, clinical patients, systemic lupus erythematosus patients, cancer patients, tumour cell derived, cardiovascular disease

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